GF5 Next Generation
GF5 Next Generation
Adopted by some of the UK’s top skin and aesthetic clinics, GF5 Growth Factor Serum has changed the industry’s beliefs in what a single serum can achieve. GF5 Next Generation contains over 18 powerful actives clinically proven to offer superior skin rejuvenation and skin barrier healing.
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From £164.59
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30ml
Adopted by some of the UK’s top skin and aesthetic clinics, GF5 Growth Factor Serum has changed the industry’s beliefs in what a single serum can achieve, both in combination with aesthetic treatments such as laser and RF microneedling, and when used alone.
GF5 Next Generation contains over 18 powerful actives clinically proven to offer superior skin rejuvenation and skin barrier healing. These include:
- Growth Factor Complex – 5 powerful bio-identical growth factors for skin repair and regeneration, capable of addressing all key signs of ageing.
- Palmitotyl Tripeptide-8 – a peptide which reduces redness, irritation and skin sensitivity.
- Copper Tripeptide-1- this ‘miracle’ peptide has collagen-boosting, anti-cancer, anti-inflammatory and cell cleansing properties.
- Neuropeptides – two clinically proven wrinkle-reducing peptides.
- 5 Ceramide Complex – based on the key ceramides found in our skin to provide intense hydration, repair skin barrier and reduce how quickly you lose moisture from your skin during your normal day to day activity(TEWL).
- Calcium alpha-hydroxymethionine & Homotaurine – help restore skin thickness, firmness, elasticity and smoothness.
Featuring a high concentration of 5 unique Growth Factors that are bio-identical to the life-giving Growth Factors found in the human placenta. When these Growth Factors are applied directly to the skin, they help to reverse the ageing process and repair existing damage by triggering processes essential for repair. Other ingredients such as Vitamin B9 support and improve Growth Factor efficacy. Our neuropeptides help to minimise and prevent lines and wrinkles.
- Addresses all key signs of skin ageing
- Promotes regeneration of damaged skin
- Repairs impaired skin barriers
- Improves overall skin health
Suitable for all skin types
Vegan
Cruelty-free
Hypo-allergenic
Dermatologist-tested
GF5 Next Generation Feature Checklist
- Wound healing
- Skin laxity
- Poor skin texture
- Red & irritated skin
- Fine lines and wrinkles
- Premature ageing
- Crepey skin
- Scarring
- Blemishes and spots
- Burns
- Stretch marks
- Promotes repair and regeneration after treatments such as:
- Micro-needling
- Radio-frequency
- LASER
- Dermal fillers
- Improves elasticity by up to 47% in 4 weeks*
- Reduces eye wrinkles by up to 46% in 4 weeks*
- Reduces recovery time post-procedure (e.g. LASER, RF-microneedling)
- Reduces complication rate post-procedure
- Enhances the results from collagen-stimulating treatments
- Significantly accelerates wound healing
- Skin appears smoother and firmer
- Minimises the appearance of fine lines and wrinkles
- Long-lasting hydration with Ceramide Complex
- Reduces pain during procedures
*Clinical study carried out on 12 females aged 43-50 in a 4 week period with CellDerma Growth Factor Complex.
CellDerma Growth Factor Complex: Growth Factors are key to our body’s ability to repair and replace damaged cells. By our late teens, our natural growth factor production begins to decline significantly. By our late 20s-30s, this is negligible. Thus, damaged skin cells are far less likely to be repaired leading to the first signs of ageing. The entire architecture of the skin changes and growth factors have the ability to effect a reversal of these changes.
One growth factor cannot do it all, however. GF5 incorporates a unique blend of 5 key factors that collectively stimulate a holistic regenerative process in the skin. Blood vessel supply improves, skin thickness increases, collagen and other key structural proteins improve in quality and quantity, and much more. GF5 is a true all-rounder and may be used by any skin type for a whole host of concerns from scarring and skin trauma (not on open skin) to skin laxity and dullness.
Palmitotyl Tripeptide-8: this innovative neuropeptide rapidly calms and soothes irritated skin, helping to restore and maintain a normal skin sensitivity threshold. It is a highly multi-functional agent that helps reduce irritation caused by UV radiation, immune reactions, internal and mechanical stress (eg shaving, laser, Morpheus8).
Copper Tripeptide-1: this ‘miracle’ peptide has multiple positive biological actions which include, stimulation of collagen and elastin production, powerful anti-inflammatory and anti-cancer effects and activation of cell cleansing, helping to normalise cell function. From wound healing to skin rejuvenation, this active is an impressive addition to the GF5 formula.
Ceramide & Cholesterol complex: Ceramides make up 50% of the stratum corneum (surface layer of the epidermis). Together with cholesterol (which makes up 25%) and saturated fatty acids, these fats create a water-impermeable skin barrier, preventing excessive water loss and shielding against environmental attack (e.g. micro-organisms). Ceramide and cholesterol levels diminish with ageing skin, leading to dry and irritated skin. GF5 (Next Generation) delivers an oil soluble complex of Ceramide 1, Ceramide 2, Ceramide 3, Ceramide 4 and Ceramide 6 present in human skin, as well as Cholesterol.
Lecithin and sodium hyaluronate (hyaluronic acid) enhance GF5’s hydrating ability further. Lecithin is rich in fatty acids (which make up 15% of the stratum corneum) and reduces TEWL.
Neuropeptides inhibit messages from nerves to muscles to reduce overactivity and slow down the formation of expression lines.
Calcium alpha-hydroxymethionine & Homotaurine, strengthen and restructure thin and fragile skin. They help restore epidermal cell function and environment, as well as protein and lipid (fat) synthesis.
Acetyl glutamine (amino acid) and Vitamin B9 work in synergy with the growth factors, further enhancing efficacy.
Apply 1-2 pumps to clean dry skin, including eyelifes, twice daily. Apply to the face and neck in an upward motion.
Suitable for pre and post-care treatment for skin procedures such as RF-microneedling, LASER, gas-plasma and surgery (e.g. blepharoplasty). Minimum 3-14 days pre-procedure and 7-28 days post-procedure. If being used for pre- or post-procedure care, please seek advice of your skin practitioner.
- 100% vegan Growth Factors
- High-quality, sustainably-sourced ingredients
- Clean science
- Cruelty-free ingredients
- Parabens
- Sulfates
- Phthalates
- Fragrances*
- Colours*
- Unnecessary chemicals and preservatives
*Trace fragrance in Perfect Lips and PHA Renewal Scrub. Coloured tint added to Tinted Mineral SPF 30.
In order to offer you the very best in skincare, we are in a constant process of product evolution. Thus, depending on when and where you purchase your product, the ingredient list shown here may differ from the product you receive. Please refer to your product packaging for ingredient information specific to your product.
Aqua (Water)
The primary solvent of most skincare products.
Glycerin
A natural compound that helps to shield the skin from the environment and avoid irritation. Promotes softness to the skin. Protects and strengthens the skin barrier. Allows other ingredients to penetrate to uppermost layers of the skin.
Carthamus Tinctorius Seed Oil
Also known as safflower oil, this is very rich in fatty acids including linoleic acid, providing excellent non-comedogenic hydration.
Butylene Glycol
Initially found in sugarcane, Butylene Glycol is used in formulations to create a smooth, thick consistency that glides effortlessly on the skin. It also helps other ingredients absorb more efficiently into the skin whilst maintaining a healthy skin barrier.
sh-Oligopeptide-1
Also known as Epidermal Growth Factor (EGF) that stimulates cell growth and healing. Accelerates wound healing, minimises the appearance of fine lines and wrinkles and helps treat acne, premature ageing and stretch marks. Hydrates and improves the elasticity of the skin.
sh-Oligopeptide-2
Also known as Insulin-Like Growth Factor(IGF-1) stimulates cell proliferation and wound healing.
sh-Polypeptide-1
Also called Basic Fibroblast Growth Factor. Stimulates fibroblast cell growth and proliferation which stimulates the synthesis of collagen. Reduces loss of water in the skin, reduces signs of ageing, improves skin hydration and accelerates skin healing response.
sh-Polypeptide-11
Also known as Acidic Fibroblast Growth Factor. Stimulates skin regeneration, wound healing, and collagen and elastin synthesis. Improves skin elasticity so the skin will feel and look smoother and firmer.
sh-Polypeptide-9
Also known as Vascular Endothelial Growth Factor. Stimulates the formation of blood vessels, supplying collagen-making cells with nutrients. Accelerates wound healing, improving the appearance of scars, wounds, burns and stretch marks.
Copper Tripeptide-1
A 'miracle' peptide which helps to regenerate sensitive or damaged skin. Powerful anti-oxidant and anti-inflammatory. Breaks down damaged collagen and boosts production of new proteins eg elastin and collagen, as well as hyaluronic acid levels.
Palmitoyl Tripeptide-8
A liponeuropeptide which reduces skin redness, irritation and overall sensitivity from any cause ie mechanical (eg LASER), internal (eg Stress), UV radiation and more. Beneficial before and after skin procedures and in generally red-prone skin.
Acetyl Hexapeptide-30
A peptide which serves to provide an anti-wrinkle injection effect. It works by blocking nerve signals that cause facial muscles to contract and form lines and wrinkles. This reduction in nerve signalling can reduce and prevent dynamic lines and wrinkles from forming. It provides anti-ageing results and should be used as a preventative for premature ageing.
Acetyl Hexapeptide-8
A peptide which serves to provide an anti-wrinkle injection e¥ect. It works by blocking nerve signals that cause facial muscles to contract and form lines and wrinkles. This reduction in nerve signalling can reduce and prevent dynamic lines and wrinkles from forming. It provides anti-ageing results and should be used as a preventative for premature ageing.
Ceramide NP
A lipid (fat) molecule essential for skin barrier integrity. A form of Ceramide 3, this is one of the most beneficial ceramides for the skin, helping to restore levels in the skin barrier.
Ceramide AP
Ceramide 6 - an essential component of the stratum corneum or uppermost layer of the epidermis, helping to lock in moisture without causing breakouts.
Ceramide AG
Ceramide 4 - an essential component of the stratum corneum or uppermost layer of the epidermis, helping to lock in moisture without causing breakouts.
Ceramide NG
Ceramide 2 - an essential component of the stratum corneum or uppermost layer of the epidermis, helping to lock in moisture without causing breakouts.
Ceramide EOP
Ceramide 1 - an essential component of the stratum corneum or uppermost layer of the epidermis, helping to lock in moisture without causing breakouts.
Arginine
An amino acid that is one of the primary building blocks for hair keratin and skin collagen.
Sodium Hyaluronate
The most absorbable form of hyaluronic acid (HA), mimicking your natural HA to attract water and also enhances penetration of other actives in your skincare regime.
Bacillus/Soybean/Folic Acid Ferment Extract
An extract from soybean helps to moisturise and brighten the skin. Also acts as a non-irritant.
Acetyl Glutamine
An organic compound that protects and reduces water loss from oxidative stress.
Lecithin
A plant-derived, water-binding ingredient which acts as an emollient to hydrate and softens the skin. It improves the retention of skin moisture and can help encapsulate active ingredients, allowing for better dermal delivery.
Hydrogenated Lecithin
A plant-derived, waterbinding ingredient which acts as an emoillent to hydrate and soften the skin. It improves the retention of skin moisture and can help encapsulate active ingredients, allowing for better dermal delivery.
Dextran
A soothing and moisture-retaining agent, dextran can also reduce puffiness.
Cholesterol
A critical component of the epidermis, this fat helps to retain moisture in the skin, promoting firmer, tighter and overall healthier skin.
Calcium Hydroxymethionine
A water-soluble compound which acts as a moisturising agent.
3-Aminopropane Sulfonic Acid
A natural amino acid found in seaweed can act as an emulsifier to help mesh water and oil within a product.
Tetrasodium Glutamate Diacetate
Naturally-derived chelating agent which boosts effectiveness of preservatives.
Glyceryl Stearate
Moisturises by forming a layer on the surface to lock in moisture, making the skin softer and smoother.
Ammonium Acryloyldimethyltaurate/VP Copolymer
A polymer that helps to create gel-like texture. prevents the product from feeling tacky or sticky.
Caprylyl Glycol
A fatty acid derived from caprylic acid boosts the effectiveness of preservatives and provides a skin-softening effect.
Polysorbate-20
A water-soluble compound emulsifier which helps bind water and oil together within a product to improve product texture.
Dipropylene Glycol
A well tolerated humectant that attracts water to help with skin hydration.
Pentylene Glycol
A multi-functional ingredient that helps skin feel silky, works as an emulsion stabiliser and antimicrobial and helps improve the water resistance of sunscreens.
1,2-Hexanediol
A synthetic preservative with moisture-binding and anti-inflammatory properties.
Hydroxyethylcellulose
Derived from cellulose, the major component of the cell wall of green plants, it provides a thick and beautiful gel-like consistency to the product.
Phenoxyethanol
A safe and gentle preservative (found in nature in Green Tea). Kills bacteria and microorganisms; prolongs shelf life.
Ethylhexylglycerin
A compound derived from grains and plants. Boosts the effectiveness of preservatives.
Potassium Sorbate
Used as a preservative to reduce the growth of bacteria, fungi, and moulds in the product.
Citric Acid
A natural anti-oxidant, citric acid also helps revive skin by evening skin tone and cleaning pores.