GF5 Next Generation

GF5 Next Generation

Adopted by some of the UK’s top skin and aesthetic clinics, GF5 Growth Factor Serum has changed the industry’s beliefs in what a single serum can achieve. GF5 Next Generation contains over 18 powerful actives clinically proven to offer superior skin rejuvenation and skin barrier healing.
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From £164.59


Adopted by some of the UK’s top skin and aesthetic clinics, GF5 Growth Factor Serum has changed the industry’s beliefs in what a single serum can achieve, both in combination with aesthetic treatments such as laser and RF microneedling, and when used alone.

GF5 Next Generation contains over 18 powerful actives clinically proven to offer superior skin rejuvenation and skin barrier healing. These include:

  • Growth Factor Complex – 5 powerful bio-identical growth factors for skin repair and regeneration, capable of addressing all key signs of ageing.
  • Palmitotyl Tripeptide-8 – a peptide which reduces redness, irritation and skin sensitivity.
  • Copper Tripeptide-1- this ‘miracle’ peptide has collagen-boosting, anti-cancer, anti-inflammatory and cell cleansing properties.
  • Neuropeptides – two clinically proven wrinkle-reducing peptides.
  • 5 Ceramide Complex – based on the key ceramides found in our skin to provide intense hydration, repair skin barrier and reduce how quickly you lose moisture from your skin during your normal day to day activity(TEWL).
  • Calcium alpha-hydroxymethionine & Homotaurine – help restore skin thickness, firmness, elasticity and smoothness.

Featuring a high concentration of 5 unique Growth Factors that are bio-identical to the life-giving Growth Factors found in the human placenta. When these Growth Factors are applied directly to the skin, they help to reverse the ageing process and repair existing damage by triggering processes essential for repair. Other ingredients such as Vitamin B9 support and improve Growth Factor efficacy. Our neuropeptides help to minimise and prevent lines and wrinkles.

  • Addresses all key signs of skin ageing
  • Promotes regeneration of damaged skin
  • Repairs impaired skin barriers
  • Improves overall skin health

Suitable for all skin types

GF5 Next Generation Feature Checklist

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  • Wound healing
  • Skin laxity
  • Poor skin texture
  • Red & irritated skin
  • Fine lines and wrinkles
  • Premature ageing
  • Crepey skin
  • Scarring
  • Blemishes and spots
  • Burns
  • Stretch marks
  • Promotes repair and regeneration after treatments such as:
    • Micro-needling
    • Radio-frequency
    • LASER
    • Dermal fillers
  • Improves elasticity by up to 47% in 4 weeks*
  • Reduces eye wrinkles by up to 46% in 4 weeks*
  • Reduces recovery time post-procedure (e.g. LASER, RF-microneedling)
  • Reduces complication rate post-procedure
  • Enhances the results from collagen-stimulating treatments
  • Significantly accelerates wound healing
  • Skin appears smoother and firmer
  • Minimises the appearance of fine lines and wrinkles
  • Long-lasting hydration with Ceramide Complex
  • Reduces pain during procedures

*Clinical study carried out on 12 females aged 43-50 in a 4 week period with CellDerma Growth Factor Complex.

CellDerma Growth Factor Complex: Growth Factors are key to our body’s ability to repair and replace damaged cells. By our late teens, our natural growth factor production begins to decline significantly. By our late 20s-30s, this is negligible. Thus, damaged skin cells are far less likely to be repaired leading to the first signs of ageing. The entire architecture of the skin changes and growth factors have the ability to effect a reversal of these changes.

One growth factor cannot do it all, however. GF5 incorporates a unique blend of 5 key factors that collectively stimulate a holistic regenerative process in the skin. Blood vessel supply improves, skin thickness increases, collagen and other key structural proteins improve in quality and quantity, and much more. GF5 is a true all-rounder and may be used by any skin type for a whole host of concerns from scarring and skin trauma (not on open skin) to skin laxity and dullness.

Palmitotyl Tripeptide-8: this innovative neuropeptide rapidly calms and soothes irritated skin, helping to restore and maintain a normal skin sensitivity threshold. It is a highly multi-functional agent that helps reduce irritation caused by UV radiation, immune reactions, internal and mechanical stress (eg shaving, laser, Morpheus8).

Copper Tripeptide-1: this ‘miracle’ peptide has multiple positive biological actions which include, stimulation of collagen and elastin production, powerful anti-inflammatory and anti-cancer effects and activation of cell cleansing, helping to normalise cell function. From wound healing to skin rejuvenation, this active is an impressive addition to the GF5 formula.

Ceramide & Cholesterol complex: Ceramides make up 50% of the stratum corneum (surface layer of the epidermis). Together with cholesterol (which makes up 25%) and saturated fatty acids, these fats create a water-impermeable skin barrier, preventing excessive water loss and shielding against environmental attack (e.g. micro-organisms). Ceramide and cholesterol levels diminish with ageing skin, leading to dry and irritated skin. GF5 (Next Generation) delivers an oil soluble complex of Ceramide 1, Ceramide 2, Ceramide 3, Ceramide 4 and Ceramide 6 present in human skin, as well as Cholesterol.

Lecithin and sodium hyaluronate (hyaluronic acid) enhance GF5’s hydrating ability further. Lecithin is rich in fatty acids (which make up 15% of the stratum corneum) and reduces TEWL.

Neuropeptides inhibit messages from nerves to muscles to reduce overactivity and slow down the formation of expression lines.

Calcium alpha-hydroxymethionine & Homotaurine, strengthen and restructure thin and fragile skin. They help restore epidermal cell function and environment, as well as protein and lipid (fat) synthesis.

Acetyl glutamine (amino acid) and Vitamin B9 work in synergy with the growth factors, further enhancing efficacy.

Apply 1-2 pumps to clean dry skin, including eyelifes, twice daily. Apply to the face and neck in an upward motion.

Suitable for pre and post-care treatment for skin procedures such as RF-microneedling, LASER, gas-plasma and surgery (e.g. blepharoplasty). Minimum 3-14 days pre-procedure and 7-28 days post-procedure. If being used for pre- or post-procedure care, please seek advice of your skin practitioner.

  • 100% vegan Growth Factors
  • High-quality, sustainably-sourced ingredients
  • Clean science
  • Cruelty-free ingredients
  • Parabens
  • Sulfates
  • Phthalates
  • Fragrances*
  • Colours*
  • Unnecessary chemicals and preservatives

*Trace fragrance in Perfect Lips and PHA Renewal Scrub. Coloured tint added to Tinted Mineral SPF 30.

In order to offer you the very best in skincare, we are in a constant process of product evolution. Thus, depending on when and where you purchase your product, the ingredient list shown here may differ from the product you receive. Please refer to your product packaging for ingredient information specific to your product.

Aqua (Water)
Carthamus Tinctorius Seed Oil
Butylene Glycol
Copper Tripeptide-1
Palmitoyl Tripeptide-8
Acetyl Hexapeptide-30
Acetyl Hexapeptide-8
Ceramide NP
Ceramide AP
Ceramide AG
Ceramide NG
Ceramide EOP
Sodium Hyaluronate
Bacillus/Soybean/Folic Acid Ferment Extract
Acetyl Glutamine
Hydrogenated Lecithin
Calcium Hydroxymethionine
3-Aminopropane Sulfonic Acid
Tetrasodium Glutamate Diacetate
Glyceryl Stearate
Ammonium Acryloyldimethyltaurate/VP Copolymer
Caprylyl Glycol
Dipropylene Glycol
Pentylene Glycol
Potassium Sorbate
Citric Acid