GF5 Next Generationยฎ

Bio-Regenerative Growth Factor Serum

£175.00
  • Global Green Beauty Awards 2024 bronze award badge recognising achievement in sustainable beauty innovation.
  • Global Green Beauty Awards 2025 silver award badge recognising excellence in green beauty and skincare.
  • Pure Beauty Awards 2024 gold winner badge for Best New Dermatological Treatment or Product.

Regenerative Support

Helps renew tired-looking skin

Redness Support

Helps calm visible redness

Anti-Aging

Helps soften visible aging

Hydration Support

Helps replenish skin moisture

Hero product image of CellDerma GF5 Bio-Regenerative Growth Factor Serum in a minimal clinical setting.

GF5 (30ml) is a clinically proven growth-factor serum designed to support skin regeneration, improve elasticity and accelerate recovery while helping restore radiance and strengthen the skin barrier.

 

Free delivery on orders ยฃ100+
Free gift on first order ยฃ50+
Close-up of CellDerma GF5 serum being dispensed onto glowing skin beside the eye and cheek area.

Award-Winning Growth Factor Serum

Winner of Best New Dermatological Product or Treatment 2024, GF5ยฎ Next Generation is an advanced growth factor serum trusted by leading UK skin and aesthetic clinics to visibly rejuvenate aging, compromised, and post-procedure skin. Designed to work alongside advanced treatments including laser and RF microneedling, this next-generation skin regeneration serum also delivers powerful standalone results for visibly healthier, stronger, more radiant-looking skin.

CellDerma GF5 serum bottle placed on a smooth white skincare texture background.

Skin Regeneration For Fine Lines & Skin Laxity

Formulated with over 18 advanced actives, GF5ยฎ Next Generation combines clinically studied ingredients known to support visible skin rejuvenation, hydration, and barrier repair. This intelligent formulation works across multiple pathways involved in skin aging, helping improve the appearance of skin laxity, crepey skin, uneven texture, fine lines, wrinkles, and sensitivity whilst promoting smoother, firmer, calmer, more balanced skin.

CellDerma GF5 Bio-Regenerative Growth Factor Serum with branded product packaging on a clean white background.

Copper Peptide Serum With Five Growth Factors

At the heart of the formula are five unique bio-identical growth factors inspired by the life-giving growth factors naturally found within the human placenta. Combined with Copper Tripeptide-1, neuropeptides, Vitamin B9, and Palmitoyl Tripeptide-8, this radiance boosting serum helps support collagen production, visible repair, pigmentation, elasticity, and skin renewal whilst helping minimise the appearance of lines and wrinkles.

Close-up of radiant healthy skin showing hydration and glow after skincare application.

Barrier Repair & Long-Lasting Hydration Support

GF5ยฎ Next Generation also features a 5 Ceramide Complex to strengthen the skin barrier, reduce transepidermal water loss (TEWL), and deliver long-lasting hydration throughout the day. Advanced actives including calcium alpha-hydroxymethionine and homotaurine further support visible firmness, elasticity, and smoother-looking skin. Lightweight yet intensely nourishing, this copper peptide serum leaves skin brighter, healthier-looking, revitalised, and visibly more youthful with continued use.


Professional headshot of Dr Dev Patel smiling in a white clinical uniform against a clean light background.
Dr. Dev Patel

GF5ยฎ Next Generation

Developed by Dr. Dev Patel
Pioneer in bio-regenerative skincare

“As we age, the biological signals that tell our skin to repair and regenerate start to slow down. One of the reasons I formulated GF5 was to help restore those signals.โ€

GF5 combines carefully selected growth factors and peptides that support the skinโ€™s natural renewal processes. I recommend it to patients who want to improve the overall quality of their skin โ€” helping it look smoother, stronger and healthier over time.

It is particularly useful for supporting collagen activity and skin regeneration, and it works very well alongside many aesthetic treatments to help the skin recover and maintain long term results.”

Real People, Real Skin, Real Results

Kellyโ€™s Story:
How GF5 Helped My Skin

โ€I really loved it. I noticed that I wasnโ€™t wearing makeup. I didnโ€™t need to put makeup on those problem areas.โ€ In this video, Kelly shares her journey using CellDermaโ€™s hero product, GF5, and why she and her friends love it.

The Important Stuff

Targets

  • Wound healing
  • Skin laxity
  • Poor skin texture
  • Red & irritated skin
  • Fine lines and wrinkles
  • Premature aging
  • Crepey skin
  • Scarring
  • Blemishes and spots
  • Burns
  • Stretch marks

Results

  • Promotes repair and regeneration after treatments such as:
    • Micro-needling
    • Radio-frequency
    • LASER
    • Dermal fillers
  • Improves elasticity by up to 47% in 4 weeks*
  • Reduces eye wrinkles by up to 46% in 4 weeks*
  • Reduces recovery time post-procedure (e.g. LASER, RF-microneedling)
  • Reduces complication rate post-procedure
  • Enhances the results from collagen-stimulating treatments
  • Significantly accelerates wound healing
  • Skin appears smoother and firmer
  • Minimises the appearance of fine lines and wrinkles
  • Long-lasting hydration with Ceramide Complex
  • Reduces pain during procedures

*Clinical study carried out on 12 females aged 43-50 in a 4 week period with CellDerma Growth Factor Complex.

How To Use

Apply 1-2 pumps to clean dry skin, including eyelids, twice daily. Apply to the face and neck in an upward motion.

Suitable for pre and post-care treatment for skin procedures such as RF-microneedling, LASER, gas-plasma and surgery (e.g. blepharoplasty). Minimum 3-14 days pre-procedure and 7-28 days post-procedure. If being used for pre- or post-procedure care, please seek advice of your skin practitioner.

Ethics

  • 100% vegan Growth Factors
  • High-quality, sustainably-sourced ingredients
  • Clean science
  • Cruelty-free ingredients

 

  • Parabens
  • Sulfates
  • Phthalates
  • Fragrances*
  • Colours
  • Unnecessary chemicals and preservatives

*Trace fragrance in Perfect Lips and PHA Renewal Scrub.

Ingredients

In order to offer you the very best in skincare, we are in a constant process of product evolution. Thus, depending on when and where you purchase your product, the ingredient list shown here may differ from the product you receive. Please refer to your product packaging for ingredient information specific to your product.

 

Aqua (Water), Glycerin, Carthamus Tinctorius Seed Oil, Butylene Glycol, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-11, sh-Polypeptide-9, Copper Tripeptide-1, Palmitoyl Tripeptide-8, Acetyl Hexapeptide-30, Acetyl Hexapeptide-8, Ceramide NP, Ceramide AP, Ceramide AG, Ceramide NG, Ceramide EOP, Arginine, Sodium Hyaluronate, Bacillus/Soybean/Folic Acid Ferment Extract, Acetyl Glutamine, Lecithin, Hydrogenated Lecithin, Dextran, Cholesterol, Calcium Hydroxymethionine, 3-Aminopropane Sulfonic Acid, Tetrasodium Glutamate Diacetate, Glyceryl Stearate, Ammonium Acryloyldimethyltaurate/VP Copolymer, Caprylyl Glycol, Polysorbate-20, Dipropylene Glycol, Pentylene Glycol, 1,2-Hexanediol, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Citric Acid.

Frequently Asked Questions

What is GF5 and what does it do?

GF5 is a bio-regenerative serum formulated with five growth factors that help support the skinโ€™s natural repair processes. It works to improve skin elasticity, reduce visible signs of aging and support overall skin quality over time.

What are growth factors and why are they important?

Growth factors are naturally occurring proteins in the skin that signal cells to repair and regenerate. As we age, these signals decline. GF5 helps restore this communication, supporting collagen production, elasticity and healthier skin function.

Who should use GF5?

GF5 is ideal for anyone concerned with signs of aging, including fine lines, wrinkles, loss of firmness and dull skin. It is also suitable for those looking to improve overall skin quality and long-term skin health.

Can GF5 be used with other skincare products?

Yes, GF5 is designed to work alongside other skincare products. It can be easily incorporated into most routines and pairs well with treatments targeting hydration, pigmentation and skin renewal.

How long does it take to see results?

Skin improvements can begin within a few weeks, with more visible changes in firmness, texture and overall skin quality typically seen with continued use over time.

Can GF5 be used after aesthetic treatments?

Yes, GF5 is often recommended to support the skin following aesthetic treatments. It helps aid recovery, supports regeneration and helps maintain results by improving overall skin quality. please seek advice of your skin practitioner. Please seek advice of your skin practitioner.

Is GF5 suitable for sensitive skin?

GF5 is formulated to be well tolerated by most skin types, including sensitive skin. It focuses on supporting the skin rather than disrupting it, making it suitable for those who may not tolerate more aggressive treatments.

Will GF5 cause irritation or peeling?

No, GF5 is not designed to exfoliate or aggressively renew the skin. Instead, it works by supporting the skinโ€™s natural processes, meaning it does not typically cause irritation, dryness or peeling.

Can GF5 replace other anti-ageing products?

GF5 can complement or, in some cases, simplify a routine by addressing multiple aspects of skin aging at once. However, it works best as part of a consistent, well-balanced skincare routine.

How should I use GF5?

Apply to clean skin using your fingertips and gently massage until absorbed. It can be used morning and evening before moisturiser as part of your daily routine.

GF5 Next Generationยฎ

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